1 edition of Uncertainties in radiation dosimetry and their impact on dose-response analyses found in the catalog.
Uncertainties in radiation dosimetry and their impact on dose-response analyses
by U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health in [Bethesda, Md.]
Written in English
|Statement||editors, Elaine Ron, F. Owen Hoffman|
|Series||NIH publication ;, no. 99-4541|
|Contributions||Ron, Elaine., Hoffman, F. Owen.|
|LC Classifications||RC268.55 .U53 1999|
|The Physical Object|
|Pagination||xi, 311 p. :|
|Number of Pages||311|
|LC Control Number||99489125|
Introduction. Assessment of radiation exposure in many epidemiologic studies of disease is subject to considerable uncertainties. When estimation of radiation exposure is based on historical reconstructions many determinates of dose may be uncertain and affect a large number of study participants simultaneously. Ionizing radiation – hazard symbol. Radiation dosimetry is the measurement, calculation and assessment of the absorbed doses and assigning those doses to individuals. It is the science and practice that attempts to quantitatively relate specific measures made in a radiation field to chemical and/or biological changes that the radiation would produce in a target.
D. C. Thomas The Utah fallout study: How uncertainty has affected estimates of dose-response. In Uncertainties in Radiation Dosimetry and Their Impact on Dose–Response Analyses (E. Ron and F. O. Hoffman, Eds.), pp. – Publication No. 99 . Songbing Qin, Miao Zhang, Sung Kim, Ting Chen, Leonard H Kim, Bruce G Haffty, Ning J Yue, A systematic approach to statistical analysis in dosimetry and patient-specific IMRT plan verification measurements, Radiation Oncology, /X, 8, 1, (), ().
The radiation dose sensitivity of dosimeter taken from slope of the linear curve of dose–response function is shown in Fig. 3. It was observed that the increase in FAC dye concentration enhanced the radiation sensitivity of the gels with a linear trend (second‐order . William Y. Song, Bryan Schaly, Glenn Bauman, Jerry J. Battista, Jake Van Dyk, Evaluation of image-guided radiation therapy (IGRT) technologies and their impact on the outcomes of hypofractionated prostate cancer treatments: A radiobiologic analysis, International Journal of Radiation Oncology*Biology*Physics, /, 64, 1.
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Uncertainties in radiation dosimetry and their impact on dose-response analyses. Bethesda, MD: National Cancer Institute; pp. – (Publication ). Thomas DC, Stram D, Dwyer J. Exposure measurement error: influence on exposure-disease relationships and methods of correction.
Ann Rev Public Health. ; –Cited by: "Proceedings of a workshop on "Uncertainties in Radiation Dosimetry and Their Impact on Dose-Response Analysis" held Septemberin Bethesda, Maryland"--Page [i]. Shipping list. Uncertainties in radiation dosimetry and their impact on dose-response analyses [microform] / editors, Elaine Ron, F.
Owen Hoffman U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute [Bethesda, Md.]. Statistical dose-response analyses in radiation epidemiology can produce misleading results if they fail to account for radiation dose uncertainties.
Abstract Schafer, D. and Gilbert, E. Some Statistical Implications of Dose Uncertainty in Radiation Dose–Response Analyses. Radiat. Res.– ().
Statistical dose–response analyse Cited by: Increasingly, efforts are being made to evaluate dosimetry uncertainties and to take account of them in statistical analyses.
The impact of these uncertainties on dose-response analyses depends on. Firstly, Lubin et al examined uncertainties in an Israeli cohort study of children exposed to radiation in the treatment of tinea capitis and the effects of uncertainties on dose–response analyses of malignant and benign thyroid tumours.
The authors found that dosimetric uncertainties were due to a variety of factors, including uncertainty. A radiation dosimeter is a device, instrument or system that measures or evaluates, either directly or indirectly, the quantities exposure, kerma, absorbed dose or equivalent dose, or their time derivatives (rates), or related quantities of ionizing radiation.
A dosimeter along with its reader is referred to as a dosimetry system. 5 year Impact Factor. Radiation Protection Dosimetry publishes peer-reviewed papers covering all aspects of personal and environmental dosimetry and monitoring for both ionising and non-ionising The Validation of Comprehensive Software for the Assessment of Radiological Impacts on Humans Through Benchmark Analysis with Radiological Codes.
morbidity. While multiple reports have defined accuracy needs in radiation oncology, most of these reports were developed in an earlier era with different radiation technologies. In the meantime, the uncertainties in radiation dosimetry reference standards have improved and more detailed patient outcome data are available.
Uncertainties in Radiation Dosimetry and their Impact on Risk Analysis was to explore how uncertainties in individual dose estimates affect the statistical power and shape of the dose response in epidemiologic investigations.
It was a follow-up of a workshop that was held by the National Cancer Institute on the same topic in September Fundamentals of Radiation Dosimetry and Radiological Physics AlexFBielajew TheUniversityofMichigan DepartmentofNuclearEngineeringandRadiologicalSciences.
Accuracy requirements in radiation oncology have been defined in multiple publications; however, these have been based on differing radiation technologies. In the meantime, the uncertainties in radiation dosimetry reference standards have been reduced and more detailed patient outcome data.
The irradiation temperature dependence of the 60 Co gamma-ray dose response of a silver-dichromate dosimeter was studied to verify temperature coefficients over 5–60°C, using both low and high range standard-type dosimeters.
The temperature coefficients in the temperature range 25–60°C are estimated to be − and −%/°C respectively at doses 2–10 kGy and 10–50 kGy. curves depending on tissue, effect, uncertainties in clinical dosimetry and in assessing outcomes, radiobiological variability, technique used, dose per fraction, etc.
At the steepest parts of the dose-response curves, and for the steepest curves, 5% changes in dose can produce % changes in TCP and % changes in NTCP. individual mean dose in their regression model . Other investigators have estimated the dose-response by treating dose uncertainties as mixtures of Berkson and random classical errors [11, ].
Few studies, however, have addressed the impact of shared (systematic) uncertainties in dose-response analysis. The analysis described here has shown that differences in most of the radiation dose estimates for the various compounds are small compared with the absolute uncertainty in their values.
The issue of risk at low doses (such as those associated with diagnostic procedures) is generally addressed with the linear, no-threshold (LNT) dose–response. Treatment of UncertaintiesTreatment of Uncertainties in Radiation Dosimetry Michael G Mitch Ph DMichael G.
Mitch, Ph.D.1 Larry A. DeWerd, Ph.D.2 Roodo, Minniti, Ph.D.1 Jeffrey F. Williamson, Ph.D. 3 1Physics Laboratory, National Institute of Standards and Technology (NIST) 2Deptartment Of Medical Physics, University of Wisconsin-Madison 3Department of Radiation.
Thus, for example, if Xmeasured uncertainties in radiation therapy • T. PADIKAL 65 A worked out example of this kind of situation is given in Appendix 2. Radiation Protection Dosimetry, VolumeIssue James Marsh, Alan Birchall, Comparison of radon lung dosimetry models for the estimation of dose uncertainties, Radiation Protection Dosimetry, VolumeIssue Such dose uncertainties have significant implications for the analysis of lung cancer data in terms of dose-effect.
ISBN X (pbk.)—ISBN (pdf) 1. Ionizing radiation—Toxicology. 2. Ionizing radiation—Physiological effect. 3. Ionizing radiation—Dose-response relationship.
I. National Research Council (U.S.). Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation.
RAR2H ′99—dcRadiation dose reconstruction systems for large-scale epidemiological studies are sophisticated both in providing estimates of dose and in representing dosimetry uncertainty.
For example, a computer program was used by the Hanford Thyroid Disease Study to provide realizations of possible dose to study participants.Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body.
This applies both internally, due to ingested or inhaled radioactive substances, or externally due to irradiation by sources of radiation.